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It acts as a non-selective melanocortin receptor agonist with the following binding profile (approximate Ki values): MC1R : ~0.67 nM (highest affinity, melanogenesis) MC4R : ~6.6 nM (appetite suppression, sexual function) MC3R : ~34 nM (energy balance) MC5R : ~46 nM (exocrine gland function) This broad receptor profile produces multiple physiological effects

95% CI: 1.46 to 0.16

individual needs and results vary

[published online ahead of print, Aug 11]

Evening primrose oil : High in gamma-linolenic acid (GLA), this oil is popular for its ability to help manage skin dryness, as well as the dryness of mucous membranes, including vaginal dryness